Abstract
Additions of organodilithium reagents to dialdehydes allow for construction of [1.1.1.1]metacyclophane macrocycle in ∼40% yield in the ring forming step, without resort to standard high dilution techniques. The present methodology is complementary to the conventional condensations leading to phenol- and resorcinol-based cyclotetramers.
Original language | English (US) |
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Pages (from-to) | 7701-7703 |
Number of pages | 3 |
Journal | Journal of Organic Chemistry |
Volume | 59 |
Issue number | 25 |
DOIs | |
State | Published - Dec 1 1994 |
ASJC Scopus subject areas
- Organic Chemistry