Synthesis of bacteriophage phi6 double stranded ribonucleic acid

D. L. Coplin, J. L. Van Etten, A. K. Vidaver

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Uracil was incorporated into all 3 bacteriophage phi6 dsRNA segments throughout the infection cycle; the rates of incorporation into each of the 3 segments were approx. constant for the first 15 to 20 min and then increased rapidly until 50 min after infection. The medium and small dsRNA segments were produced in greater amounts than the large dsRNA segment at all times in the infection cycle. Inhibition of host RNA and protein synthesis with rifampin and chloramphenicol revealed that virus dsRNA synthesis immediately after infection was independent of either host function.

Original languageEnglish (US)
Pages (from-to)509-512
Number of pages4
JournalJournal of General Virology
Volume33
Issue number3
DOIs
StatePublished - 1976

ASJC Scopus subject areas

  • Virology

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