@inbook{b0ddc39896b0484986562a1b2a3dde5b,
title = "Synthesis of bioreducible polycations with controlled topologies",
abstract = "Bioreducible polycations, which possess disul fi de linkages in the backbone, have appeared as promising gene delivery carriers due to their high stability in extracellular physiological condition and bioreductiontriggered release of genetic materials, as well as reduced cytotoxicity because intracellular cytosol is a reducing environment containing high level of reducing molecules such as glutathione. Here, we describe the syntheses of bioreducible polycations, and the methods for control over their topology are also presented.",
keywords = "Bioreducible polycations, Controlled topologies, Michael-Addition polymerization, Poly(2-(dimethylamino)ethyl methacrylate), Poly(amido amine)s, Polyethylenimine",
author = "You, {Ye Zi} and Yan, {Jun Jie} and Yu, {Zhi Qiang} and David Oupicky",
year = "2013",
doi = "10.1007/978-1-62703-140-0_9",
language = "English (US)",
isbn = "9781627031394",
series = "Methods in Molecular Biology",
publisher = "Humana Press Inc.",
pages = "121--132",
booktitle = "Nanotechnology for Nucleic Acid Delivery",
}