Abstract
Highly enantioselective rhodium-catalyzed hydroboration of allylic phosphonates by pinacolborane affords chiral tertiary boronic esters. The β-borylated phosphonates are readily converted to chiral β- and γ-hydroxyphosphonates and aminophosphonates and to phosphonates bearing a quaternary carbon stereocenter. The utility of the latter is illustrated by the synthesis of (S)-(+)-bakuchiol methyl ether.
Original language | English (US) |
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Pages (from-to) | 6066-6069 |
Number of pages | 4 |
Journal | Journal of the American Chemical Society |
Volume | 139 |
Issue number | 17 |
DOIs | |
State | Published - May 3 2017 |
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)
- Biochemistry
- Colloid and Surface Chemistry