Synthesis of spiro-bisperoxyketals

Prasanta Ghorai, Patrick H. Dussault, Chunhua Hu

Research output: Contribution to journalArticlepeer-review

76 Scopus citations


(Chemical Equation Presented) Syntheses of spirocyclic bis-1,2-dioxolanes, bis-1,2-dioxanes, and bis-1,2-dioxepanes are achieved through intramolecular ketalizations of hydroperoxy ketones or intramolecular alkylations of gem-dihydroperoxides. The spiroperoxides have excellent thermal and chemical stability, and several display promising activity against P. falciparum.

Original languageEnglish (US)
Pages (from-to)2401-2404
Number of pages4
JournalOrganic Letters
Issue number12
StatePublished - 2008

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry


Dive into the research topics of 'Synthesis of spiro-bisperoxyketals'. Together they form a unique fingerprint.

Cite this