Synthesis of star-like poly[N-(2-hydroxypropyl)methacrylamide] using PAMAM dendrimer as the core

Dong Wang, Pavla Kapečková, Tamara Minko, Vajira Nanayakkara, Jindrich Kopeček

Research output: Contribution to journalConference articlepeer-review

9 Scopus citations

Abstract

The synthesis of star-like polyhydroxypropyl methacrylamide (HPMA) copolymers using StarburstTM (PAMAM) dendrimers as the core is described. The star-like polymers were characterized by size exclusion chromatography, matrix assisted desorption/ionization-mass spectrometry, 1H nuclear magnetic resonance and ultraviolet spectroscopy. Doxorubicin was introduced into the star polymer to verify their potential for a new anticancer drug delivery system.

Original languageEnglish (US)
Pages (from-to)994-995
Number of pages2
JournalAmerican Chemical Society, Polymer Preprints, Division of Polymer Chemistry
Volume41
Issue number1
StatePublished - Mar 2000
Externally publishedYes
EventThe San Francisco Meeting - San Francisco, CA, USA
Duration: Mar 26 2000Mar 31 2000

ASJC Scopus subject areas

  • Polymers and Plastics

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