Projeto de célula-T: Estudo internacional, longitudinal de pacientes com linfoma de célula-T periférica agressivo

Translated title of the contribution: T-Cell project: An international, longitudinal, observational study of patients with aggressive peripheral T-cell lymphoma

Massimo Federico, Monica Bellei, Emanuela Pesce, Emanuele Zucca, Stefano Pileri, Silvia Montoto, Dennis D. Weisenburger, Thomas Ruediger, Y. H. Ko, Raymond Liang, Pier L. Zinzani, Joseph M. Connors, Francine M. Foss, Steven M. Horwitz, Aaron Polliack, Julie M. Vose

Research output: Contribution to journalReview article

5 Scopus citations

Abstract

Peripheral T-cell lymphomas (PTCLs) comprise a heterogeneous group of neoplasms that are derived from post-thymic lymphoid cells at different stages of differentiation and with different morphological patterns, phenotypes, and clinical presentations. PTCLs are highly diverse, reflecting the diverse cells from which they can originate and are currently sub-classified using World Health Organization (WHO) 2008 criteria. Peripheral T-Cell Lymphomas account for 5%-10% of all lymphoproliferative disorders in the Western hemisphere, with an overall incidence of 0.5-2 per 100,000 individuals per year, and have a striking epidemiological distribution, with higher incidence in Asia. The clinical features of PTCL are extremely heterogeneous. PTCLs express even more clinical diversity than B-cell non-Hodgkin's lymphomas, and there is a close, though not absolute, relationship between some unusual clinical features and certain histological subtypes.

Translated title of the contributionT-Cell project: An international, longitudinal, observational study of patients with aggressive peripheral T-cell lymphoma
Original languagePortuguese
Pages (from-to)21-25
Number of pages5
JournalRevista Brasileira de Hematologia e Hemoterapia
Volume31
Issue numberSUPPL. 2
DOIs
StatePublished - 2009

Keywords

  • Chemotherapy
  • Epidemiology
  • Outcome
  • T-cell lymphoma

ASJC Scopus subject areas

  • Hematology

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    Federico, M., Bellei, M., Pesce, E., Zucca, E., Pileri, S., Montoto, S., Weisenburger, D. D., Ruediger, T., Ko, Y. H., Liang, R., Zinzani, P. L., Connors, J. M., Foss, F. M., Horwitz, S. M., Polliack, A., & Vose, J. M. (2009). Projeto de célula-T: Estudo internacional, longitudinal de pacientes com linfoma de célula-T periférica agressivo. Revista Brasileira de Hematologia e Hemoterapia, 31(SUPPL. 2), 21-25. https://doi.org/10.1590/s1516-84842009000800007