Taste quality and extinction of a conditioned taste aversion in rats

Rick A. Bevins, Heather C. Jensen, Todd S. Hinze, Joyce Besheer

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Rats (Rattus norvegicus) that received a taste cue (saccharin, saline, quinine, or sucrose) paired with a lithium chloride (LiCl) injection displayed a robust decrease in consumption of that taste, relative to controls that had the taste unpaired with LiCl. Consumption of the paired taste increased with each nonreinforced presentation (i.e., extinction). After asymptotic extinction, rats that had had a 0.1% saccharin cue paired with LiCl consumed less of the saccharin solution than did controls. A similar data pattern was observed with a 10% sucrose solution. These results are consistent with the view that some aspect of the excitatory CS-US association remains after extinction. On the other hand, rats that had a bitter (0.005% or 0.001% quinine) or salty (1% or 0.5% saline) solution paired with LiCl drank similar amounts of the fluid as controls after asymptotic extinction treatment. Together, these experiments suggest that a taste that is either sweet or preferred is required in order to demonstrate the chronic decrease in fluid consumption after extinction treatment. The data suggest that the conditioning experience prevents the later development of a preference for the sweet taste, rather than there being a retained aversion that suppresses fluid consumption.

Original languageEnglish (US)
Pages (from-to)358-366
Number of pages9
JournalAnimal Learning and Behavior
Volume27
Issue number3
DOIs
StatePublished - Aug 1999

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Experimental and Cognitive Psychology
  • Animal Science and Zoology
  • Psychology(all)
  • Behavioral Neuroscience

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