The acid response network of Staphylococcus aureus

Chunyi Zhou, Paul D. Fey

Research output: Contribution to journalReview articlepeer-review

20 Scopus citations

Abstract

Staphylococcus aureus colonizes or causes infection in a multitude of niches within a mammalian host. Many of these niches are acidic, yet specific pH resistance mechanisms that facilitate survival have not been thoroughly investigated. This review discusses recent studies documenting known acid resistance mechanisms in S. aureus and other staphylococcal species. However, studies that clearly define the regulation of the acid resistance regulon and potential interactions with weak organic acids in specific niches of the host including the skin and gut are yet to be defined.

Original languageEnglish (US)
Pages (from-to)67-73
Number of pages7
JournalCurrent Opinion in Microbiology
Volume55
DOIs
StatePublished - Jun 2020

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)
  • Infectious Diseases

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