The American experience with transplantation for acute liver failure

Timothy M. McCashland, Byers W. Shaw, Elizabeth Tape

Research output: Contribution to journalReview articlepeer-review

70 Scopus citations


Liver transplantation has become the major therapy for acute liver failure (ALF) in the United States. Survival rates range from 46% to 89%. Appropriate patient selection, timely referral, and management of common complications have improved survival. Donor organ shortage may prompt further use of extracorporeal support systems and auxiliary transplantation in the future. This article reviews the American experience of liver transplantation in patients with ALF.

Original languageEnglish (US)
Pages (from-to)427-433
Number of pages7
JournalSeminars in liver disease
Issue number4
StatePublished - 1996


  • fulminant
  • hepatic failure
  • transplantation

ASJC Scopus subject areas

  • Hepatology


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