TY - JOUR
T1 - The Autism Diagnostic Observation Schedule, Module 4
T2 - Application of the Revised Algorithms in an Independent, Well-Defined, Dutch Sample (n = 93)
AU - de Bildt, Annelies
AU - Sytema, Sjoerd
AU - Meffert, Harma
AU - Bastiaansen, Jojanneke A.C.J.
N1 - Funding Information:
HM was supported by the Intramural Research Program of the National Institute of Mental Health, National Institutes of Health (1-ZIA-MH002860-08). The authors wish to thank all participants for their time and effort. Additionally, we thank Lentis, Groningen (Autism Team North Netherlands and WWA); FPC Dr. S. van Mesdag, Groningen; FPC Veldzicht, Balkbrug; and GGZ Drenthe, Assen (Psychosencircuit) for the support in recruitment and assessment of the participants.
PY - 2016/1/1
Y1 - 2016/1/1
N2 - This study examined the discriminative ability of the revised Autism Diagnostic Observation Schedule module 4 algorithm (Hus and Lord in J Autism Dev Disord 44(8):1996–2012, 2014) in 93 Dutch males with Autism Spectrum Disorder (ASD), schizophrenia, psychopathy or controls. Discriminative ability of the revised algorithm ASD cut-off resembled the original algorithm ASD cut-off: highly specific for psychopathy and controls, lower sensitivity than Hus and Lord (2014; i.e. ASD.61, AD.53). The revised algorithm AD cut-off improved sensitivity over the original algorithm. Discriminating ASD from schizophrenia was still challenging, but the better-balanced sensitivity (.53) and specificity (.78) of the revised algorithm AD cut-off may aide clinicians’ differential diagnosis. Findings support using the revised algorithm, being conceptually conform the other modules, thus improving comparability across the lifespan.
AB - This study examined the discriminative ability of the revised Autism Diagnostic Observation Schedule module 4 algorithm (Hus and Lord in J Autism Dev Disord 44(8):1996–2012, 2014) in 93 Dutch males with Autism Spectrum Disorder (ASD), schizophrenia, psychopathy or controls. Discriminative ability of the revised algorithm ASD cut-off resembled the original algorithm ASD cut-off: highly specific for psychopathy and controls, lower sensitivity than Hus and Lord (2014; i.e. ASD.61, AD.53). The revised algorithm AD cut-off improved sensitivity over the original algorithm. Discriminating ASD from schizophrenia was still challenging, but the better-balanced sensitivity (.53) and specificity (.78) of the revised algorithm AD cut-off may aide clinicians’ differential diagnosis. Findings support using the revised algorithm, being conceptually conform the other modules, thus improving comparability across the lifespan.
KW - Adults
KW - Assessment
KW - Autism Spectrum Disorder
KW - Classification
KW - Psychopathy
KW - Schizophrenia
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U2 - 10.1007/s10803-015-2532-4
DO - 10.1007/s10803-015-2532-4
M3 - Article
C2 - 26319249
AN - SCOPUS:84953837852
VL - 46
SP - 21
EP - 30
JO - Journal of Autism and Developmental Disorders
JF - Journal of Autism and Developmental Disorders
SN - 0162-3257
IS - 1
ER -