The chemistry and biological effects of malondialdehyde-acetaldehyde adducts

G. M. Thiele; S. Worrall; D. J. Tuma; L. W. Klassen; T. A. Wyatt; N. Nagata

doi:10.1111/j.1530-0277.2001.tb02399.x

The chemistry and biological effects of malondialdehyde-acetaldehyde adducts

G. M. Thiele, S. Worrall, D. J. Tuma, L. W. Klassen, T. A. Wyatt, N. Nagata

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Abstract

This article represents the proceedings of a workshop at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were Geoffrey M. Thiele and Simon Worrall. The presentations were (1) The chemistry of malondialdehyde-acetaldehyde (MAA) adducts, by Dean J. Tuma; (2) The formation and clearance of MAA adducts in ethanol-fed rats, by Simon Worrall; (3) Immune responses to MAA adducts may play a role in the development of alcoholic liver disease, by Lynell W. Klassen; (4) Unique biological responses to MAA-modified proteins that may play a role in the development and/or progression of alcoholic liver disease, by Geoffrey M. Thiele; (5) MAA-adducted bovine serum albumin activates protein kinase C and stimulates interleukin-8 release in bovine bronchial epithelial cells, by Todd A. Wyatt; and (6) An enzyme immune assay for serum antiacetaldehyde adduct antibody using low-density lipoprotein-adduct and its significance in alcoholic liver injury and ALDH2 heterozygotes, by Naruhiko Nagata.

Original language	English (US)
Pages (from-to)	218S-224S
Journal	Alcoholism: Clinical and Experimental Research
Volume	25
Issue number	5 SUPPL.
DOIs	https://doi.org/10.1111/j.1530-0277.2001.tb02399.x
State	Published - 2001

Keywords

Alcoholic Liver Disease
Ethanol
Malondialdehyde-Acetaldehyde
Protein Kinase C
Rats

ASJC Scopus subject areas

Medicine (miscellaneous)
Toxicology
Psychiatry and Mental health

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10.1111/j.1530-0277.2001.tb02399.x

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abstract = "This article represents the proceedings of a workshop at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were Geoffrey M. Thiele and Simon Worrall. The presentations were (1) The chemistry of malondialdehyde-acetaldehyde (MAA) adducts, by Dean J. Tuma; (2) The formation and clearance of MAA adducts in ethanol-fed rats, by Simon Worrall; (3) Immune responses to MAA adducts may play a role in the development of alcoholic liver disease, by Lynell W. Klassen; (4) Unique biological responses to MAA-modified proteins that may play a role in the development and/or progression of alcoholic liver disease, by Geoffrey M. Thiele; (5) MAA-adducted bovine serum albumin activates protein kinase C and stimulates interleukin-8 release in bovine bronchial epithelial cells, by Todd A. Wyatt; and (6) An enzyme immune assay for serum antiacetaldehyde adduct antibody using low-density lipoprotein-adduct and its significance in alcoholic liver injury and ALDH2 heterozygotes, by Naruhiko Nagata.",

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AU - Nagata, N.

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The chemistry and biological effects of malondialdehyde-acetaldehyde adducts

Abstract

Keywords

ASJC Scopus subject areas

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