The DNA polymerase gene from chlorella viruses PBCV-1 and NY-2A contains an intron with nuclear splicing sequences

Reingard Grabherr, Peter Strasser, James L. Van Etten

Research output: Contribution to journalArticle

46 Scopus citations

Abstract

The deduced amino acid sequences of two eukaryotic chlorella virus (PBCV-1 and NY-2A) DNA polymerases are 90% identical and contain amino acid motifs typical of alpha-like (Family B) DNA polymerases. The open reading frames of both PBCV-1 and NY-2A DNA polymerases are interrupted by an identically located, small (101 or 86 nucleotides, respectively) intron that resembles eukaryotic nuclear-spliced messenger RNA introns. This discovery suggests that chlorella virus replication has a nuclear phase.

Original languageEnglish (US)
Pages (from-to)721-731
Number of pages11
JournalVirology
Volume188
Issue number2
DOIs
StatePublished - Jun 1992

ASJC Scopus subject areas

  • Virology

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