The effect of acute ethanol challenge on global visuospatial attention: Exaggeration of leftward bias in line bisection

Lynnette Leone, Mark E. McCourt

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Acute alcohol challenge has been associated with a selective impairment of right hemisphere function. A hallmark of visuospatial neglect syndrome is that patients with right hemisphere lesions misbisect horizontal lines far rightward of veridical centre. Neurologically intact participants misbisect lines with a systematic leftward bias (pseudoneglect). Neuroimaging studies in neurologically intact participants reveal predominant right hemisphere activation during performance of line bisection tasks. The current study assessed whether acute alcohol challenge alters global visuospatial attention. Participants (N=18; 10 male; strongly right-handed; mean age 23 years) engaged in a forced-choice tachistoscopic line bisection task in both ethanol challenge (mean BAC=.077) and no ethanol control conditions. Mean leftward bisection error in the control condition was -0.238 degrees visual angle (1.05% line length), and leftward bisection error significantly increased (p=.001) under ethanol challenge (-0.333 degrees visual angle, 1.47% line length). Mean bisection precision in the control condition was 0.358 degrees visual angle (1.58% line length); bisection precision significantly deteriorated (p=.008) under ethanol challenge (0.489 degrees, 2.17% line length). Decreased bisection precision indicates that ethanol disrupts the fidelity of visuospatial performance. The exaggerated leftward bisection error implies that ethanol may exert a differential effect on left versus right hemispheric function with respect to the control of global visuospatial attention.

Original languageEnglish (US)
Pages (from-to)327-342
Number of pages16
JournalLaterality
Volume15
Issue number3
DOIs
StatePublished - May 2010
Externally publishedYes

Keywords

  • Ethanol
  • Line bisection
  • Pseudoneglect
  • Visuospatial attention

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Psychology(all)

Fingerprint Dive into the research topics of 'The effect of acute ethanol challenge on global visuospatial attention: Exaggeration of leftward bias in line bisection'. Together they form a unique fingerprint.

Cite this