The Effect of Early-Life Seizures on Cognitive and Motor Development: A Case Series

Sandra Jensen-Willett; Andrea Cunha; Michele A. Lobo; Regina Harbourne; Stacey C. Dusing; Sarah W. McCoy; Natalie A. Koziol; Lin Ya Hsu; Emily C. Marcinowski; Iryna Babik; Mihee An; James A. Bovaird

doi:10.1097/PEP.0000000000000918

The Effect of Early-Life Seizures on Cognitive and Motor Development: A Case Series

Sandra Jensen-Willett, Andrea Cunha, Michele A. Lobo, Regina Harbourne, Stacey C. Dusing, Sarah W. McCoy, Natalie A. Koziol, Lin Ya Hsu, Emily C. Marcinowski, Iryna Babik, Mihee An, James A. Bovaird

Research output: Contribution to journal › Article › peer-review

Abstract

Purpose: This case series documents developmental changes over time and in response to a novel intervention, Sitting Together and Reaching to Play (START-Play), in children with early-life seizures. Methods: Thirteen children with early-life seizures were included from a subset of participants in the START-Play multisite, randomized controlled trial. Seven received 3 months of twice weekly START-Play intervention; 6 continued with usual care early intervention. Bayley Scales of Infant Development-III (Cognitive Composite), Gross Motor Function Measure-66 Item Set, Assessment of Problem-Solving in Play, and reaching assessments were administered at baseline, 3, 6, and 12 months postbaseline. Change scores are reported at 3 and 12 months postbaseline. Results: Over time, plateau or decline was noted in standardized cognition measures; motor development improved or was stable. Children receiving START-Play showed positive trends in problem-solving (71.4%) and reaching behaviors (57.2%). Conclusions: Interventions such as START-Play that combine motor and cognitive constructs may benefit children with early-life seizures.

Original language	English (US)
Pages (from-to)	425-431
Number of pages	7
Journal	Pediatric Physical Therapy
Volume	34
Issue number	3
DOIs	https://doi.org/10.1097/PEP.0000000000000918
State	Published - Jul 1 2022

Keywords

development
early intervention
seizures

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Physical Therapy, Sports Therapy and Rehabilitation

Access to Document

10.1097/PEP.0000000000000918

Cite this

@article{8b6b80fd6774468cb8249c45f68d2b42,

title = "The Effect of Early-Life Seizures on Cognitive and Motor Development: A Case Series",

abstract = "Purpose: This case series documents developmental changes over time and in response to a novel intervention, Sitting Together and Reaching to Play (START-Play), in children with early-life seizures. Methods: Thirteen children with early-life seizures were included from a subset of participants in the START-Play multisite, randomized controlled trial. Seven received 3 months of twice weekly START-Play intervention; 6 continued with usual care early intervention. Bayley Scales of Infant Development-III (Cognitive Composite), Gross Motor Function Measure-66 Item Set, Assessment of Problem-Solving in Play, and reaching assessments were administered at baseline, 3, 6, and 12 months postbaseline. Change scores are reported at 3 and 12 months postbaseline. Results: Over time, plateau or decline was noted in standardized cognition measures; motor development improved or was stable. Children receiving START-Play showed positive trends in problem-solving (71.4%) and reaching behaviors (57.2%). Conclusions: Interventions such as START-Play that combine motor and cognitive constructs may benefit children with early-life seizures.",

keywords = "development, early intervention, seizures",

author = "Sandra Jensen-Willett and Andrea Cunha and Lobo, {Michele A.} and Regina Harbourne and Dusing, {Stacey C.} and McCoy, {Sarah W.} and Koziol, {Natalie A.} and Hsu, {Lin Ya} and Marcinowski, {Emily C.} and Iryna Babik and Mihee An and Bovaird, {James A.}",

note = "Funding Information: Grant Support: The study was supported by the Institute of Education Sciences. Publisher Copyright: {\textcopyright} 2022 Lippincott Williams and Wilkins. All rights reserved.",

year = "2022",

month = jul,

day = "1",

doi = "10.1097/PEP.0000000000000918",

language = "English (US)",

volume = "34",

pages = "425--431",

journal = "Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association",

issn = "0898-5669",

publisher = "Lippincott Williams and Wilkins",

number = "3",

}

TY - JOUR

T1 - The Effect of Early-Life Seizures on Cognitive and Motor Development

T2 - A Case Series

AU - Jensen-Willett, Sandra

AU - Cunha, Andrea

AU - Lobo, Michele A.

AU - Harbourne, Regina

AU - Dusing, Stacey C.

AU - McCoy, Sarah W.

AU - Koziol, Natalie A.

AU - Hsu, Lin Ya

AU - Marcinowski, Emily C.

AU - Babik, Iryna

AU - An, Mihee

AU - Bovaird, James A.

PY - 2022/7/1

Y1 - 2022/7/1

N2 - Purpose: This case series documents developmental changes over time and in response to a novel intervention, Sitting Together and Reaching to Play (START-Play), in children with early-life seizures. Methods: Thirteen children with early-life seizures were included from a subset of participants in the START-Play multisite, randomized controlled trial. Seven received 3 months of twice weekly START-Play intervention; 6 continued with usual care early intervention. Bayley Scales of Infant Development-III (Cognitive Composite), Gross Motor Function Measure-66 Item Set, Assessment of Problem-Solving in Play, and reaching assessments were administered at baseline, 3, 6, and 12 months postbaseline. Change scores are reported at 3 and 12 months postbaseline. Results: Over time, plateau or decline was noted in standardized cognition measures; motor development improved or was stable. Children receiving START-Play showed positive trends in problem-solving (71.4%) and reaching behaviors (57.2%). Conclusions: Interventions such as START-Play that combine motor and cognitive constructs may benefit children with early-life seizures.

AB - Purpose: This case series documents developmental changes over time and in response to a novel intervention, Sitting Together and Reaching to Play (START-Play), in children with early-life seizures. Methods: Thirteen children with early-life seizures were included from a subset of participants in the START-Play multisite, randomized controlled trial. Seven received 3 months of twice weekly START-Play intervention; 6 continued with usual care early intervention. Bayley Scales of Infant Development-III (Cognitive Composite), Gross Motor Function Measure-66 Item Set, Assessment of Problem-Solving in Play, and reaching assessments were administered at baseline, 3, 6, and 12 months postbaseline. Change scores are reported at 3 and 12 months postbaseline. Results: Over time, plateau or decline was noted in standardized cognition measures; motor development improved or was stable. Children receiving START-Play showed positive trends in problem-solving (71.4%) and reaching behaviors (57.2%). Conclusions: Interventions such as START-Play that combine motor and cognitive constructs may benefit children with early-life seizures.

KW - development

KW - early intervention

KW - seizures

UR - http://www.scopus.com/inward/record.url?scp=85134083551&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85134083551&partnerID=8YFLogxK

U2 - 10.1097/PEP.0000000000000918

DO - 10.1097/PEP.0000000000000918

M3 - Article

C2 - 35703307

AN - SCOPUS:85134083551

VL - 34

SP - 425

EP - 431

JO - Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association

JF - Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association

SN - 0898-5669

IS - 3

ER -

The Effect of Early-Life Seizures on Cognitive and Motor Development: A Case Series

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this