TY - JOUR
T1 - The effect of nonpharmaceutical weight-loss interventions in rural patients with diabetes
T2 - RE-POWER Diabetes
AU - Desouza, Cyrus V.
AU - Johnson-Rabbett, Brianna E.
AU - Gajewski, Byron
AU - Brown, Alexandra
AU - Ellerbeck, Edward F.
AU - VanWormer, Jeffrey J.
AU - Befort, Christie
N1 - Publisher Copyright:
© 2022 The Obesity Society (TOS). This article has been contributed to by US Government employees and their work is in the public domain in the USA.
PY - 2022/4
Y1 - 2022/4
N2 - Objective: In this secondary analysis of the Rural Engagement in Primary Care for Optimizing Weight Reduction (RE-POWER) randomized trial, the authors determined the effectiveness of weight-loss interventions in people with diabetes compared with those without diabetes living in rural areas. Methods: The RE-POWER study was a randomized trial designed to determine the effectiveness of nonpharmacological behavioral weight-loss interventions in rural participants with obesity, comparing the individual in-clinic visit model to in-person group sessions and phone group sessions over 24 months. In this secondary analysis, weight loss was compared in participants with and without diabetes. The effects of factors such as medications, insulin, and behavioral factors were compared. Results: Participants with diabetes were less likely to lose weight during the study compared with those without diabetes up to 18 months (4.12% vs. 5.31%; net difference = 1.46%; 95% CI: 0.63%-2.28%). Participants with diabetes on insulin lost less weight than patients with diabetes not on insulin at 6 months (4.52% vs. 6.88%; net difference = 2.35%; 95% CI: 0.55%-4.16%). The group with diabetes had significantly lower changes in blood pressure and lipid parameters versus the group without diabetes. Conclusions: Patients with diabetes in rural areas were less likely to lose weight, and metabolic parameters were less responsive to weight loss, compared with patients without diabetes.
AB - Objective: In this secondary analysis of the Rural Engagement in Primary Care for Optimizing Weight Reduction (RE-POWER) randomized trial, the authors determined the effectiveness of weight-loss interventions in people with diabetes compared with those without diabetes living in rural areas. Methods: The RE-POWER study was a randomized trial designed to determine the effectiveness of nonpharmacological behavioral weight-loss interventions in rural participants with obesity, comparing the individual in-clinic visit model to in-person group sessions and phone group sessions over 24 months. In this secondary analysis, weight loss was compared in participants with and without diabetes. The effects of factors such as medications, insulin, and behavioral factors were compared. Results: Participants with diabetes were less likely to lose weight during the study compared with those without diabetes up to 18 months (4.12% vs. 5.31%; net difference = 1.46%; 95% CI: 0.63%-2.28%). Participants with diabetes on insulin lost less weight than patients with diabetes not on insulin at 6 months (4.52% vs. 6.88%; net difference = 2.35%; 95% CI: 0.55%-4.16%). The group with diabetes had significantly lower changes in blood pressure and lipid parameters versus the group without diabetes. Conclusions: Patients with diabetes in rural areas were less likely to lose weight, and metabolic parameters were less responsive to weight loss, compared with patients without diabetes.
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U2 - 10.1002/oby.23392
DO - 10.1002/oby.23392
M3 - Article
C2 - 35275606
AN - SCOPUS:85126005011
SN - 1930-7381
VL - 30
SP - 884
EP - 892
JO - Obesity
JF - Obesity
IS - 4
ER -