The effect of poly (glycerol sebacate) incorporation within hybrid chitin-lignin sol-gel nanofibrous scaffolds

Tuerdimaimaiti Abudula, Lassaad Gzara, Giovanna Simonetti, Ahmed Alshahrie, Numan Salah, Pierfrancesco Morganti, Angelo Chianese, Afsoon Fallahi, Ali Tamayol, Sidi A. Bencherif, Adnan Memic

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


Chitin and lignin primarily accumulate as bio-waste resulting from byproducts of crustacean crusts and plant biomass. Recently, their use has been proposed for diverse and unique bioengineering applications, amongst others. However, their weak mechanical properties need to be improved in order to facilitate their industrial utilization. In this paper, we fabricated hybrid fibers composed of a chitin-lignin (CL)-based sol-gel mixture and elastomeric poly (glycerol sebacate) (PGS) using a standard electrospinning approach. Obtained results showed that PGS could be coherently blended with the sol-gel mixture to form a nanofibrous scaffold exhibiting remarkable mechanical performance and improved antibacterial and antifungal activity. The developed hybrid fibers showed promising potential in advanced biomedical applications such as wound care products. Ultimately, recycling these sustainable biopolymers and other bio-wastes alike could propel a "greener" economy.

Original languageEnglish (US)
Article number451
Issue number3
StatePublished - Mar 19 2018


  • Chitin-lignin
  • Electrospinning
  • Hybrid nanofiber
  • Mechanical properties
  • PGS
  • Sol-gel composite

ASJC Scopus subject areas

  • General Materials Science
  • Condensed Matter Physics


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