The effects of irradiation on the haematopoietic tissues of anaesthetized mice

A. C. Riche, J. G. Sharp, V. Littlewood, D. Thomas

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

The effects of irradiation on the haematopoietic tissues of anaesthetized mice were measured using the balance between damage and recovery during the 10 day period following the administration of various doses of whole body X irradiation. The cellularity of the femoral bone marrow, the weight of the spleen and the number of (endogenous) spleen colonies are elevated in animals anaesthetized using Avertin during exposure to doses of whole body X irradiation in the range between 400 and 850 rad, with a dose reduction factor of 1.2 to 1.4.

Original languageEnglish (US)
Pages (from-to)50-55
Number of pages6
JournalActa Haematologica
Volume50
Issue number1
DOIs
StatePublished - 1973

ASJC Scopus subject areas

  • Hematology

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