TY - JOUR
T1 - The evolving potential of companion diagnostics
AU - Khoury, Joseph D.
N1 - Publisher Copyright:
© 2016 Medisinsk Fysiologisk Forenings Forlag (MFFF).
PY - 2016/7/13
Y1 - 2016/7/13
N2 - The scope of companion diagnostics in cancer has undergone significant shifts in the past few years, with increased development of targeted therapies and novel testing platforms. This has provided new opportunities to effect unprecedented paradigm shifts in the application of personalized medicine principles for patients with cancer. These shifts involve assay platforms, analytes, regulations, and therapeutic approaches. As opportunities involving each of these facets of companion diagnostics expand, close collaborations between key stakeholders should be enhanced to ensure optimal performance characteristics and patient outcomes.
AB - The scope of companion diagnostics in cancer has undergone significant shifts in the past few years, with increased development of targeted therapies and novel testing platforms. This has provided new opportunities to effect unprecedented paradigm shifts in the application of personalized medicine principles for patients with cancer. These shifts involve assay platforms, analytes, regulations, and therapeutic approaches. As opportunities involving each of these facets of companion diagnostics expand, close collaborations between key stakeholders should be enhanced to ensure optimal performance characteristics and patient outcomes.
KW - Cancer
KW - companion diagnostics
KW - molecular diagnostics
KW - next-generation sequencing
UR - http://www.scopus.com/inward/record.url?scp=84978648899&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84978648899&partnerID=8YFLogxK
U2 - 10.1080/00365513.2016.1206444
DO - 10.1080/00365513.2016.1206444
M3 - Article
C2 - 27433788
AN - SCOPUS:84978648899
SN - 0036-5513
VL - 76
SP - S22-S25
JO - Scandinavian Journal of Clinical and Laboratory Investigation
JF - Scandinavian Journal of Clinical and Laboratory Investigation
ER -