THE GENETICS OF AN EXPANDED SECRETOR SYSTEM

W. J. Kimberling

doi:10.1111/j.1744-313X.1979.tb00332.x

THE GENETICS OF AN EXPANDED SECRETOR SYSTEM

W. J. Kimberling

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

The genetics of salivary secretion of ABH blood group substance was investigated. Eight secretor phenotypes were determined by Sephadex G‐100 chromatography. Presence or absence of three different fractions were shown to be controlled by three different secretor gene loci. These loci are called Sec₁, Sec₂ and Sec₃. Sec₁ controls expression of the traditional secretor status. Sec₂ and Sec₃ are linked, but distinct, loci controlling the expression of low molecular weight ABH substance in human saliva. A dominant mode of inheritance for the Sec₂ and Sec₃ systems is described.

Original language	English (US)
Pages (from-to)	75-82
Number of pages	8
Journal	International Journal of Immunogenetics
Volume	6
Issue number	2
DOIs	https://doi.org/10.1111/j.1744-313X.1979.tb00332.x
State	Published - Apr 1979
Externally published	Yes

ASJC Scopus subject areas

Immunology
Molecular Biology
Genetics
Genetics(clinical)

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10.1111/j.1744-313X.1979.tb00332.x

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AB - The genetics of salivary secretion of ABH blood group substance was investigated. Eight secretor phenotypes were determined by Sephadex G‐100 chromatography. Presence or absence of three different fractions were shown to be controlled by three different secretor gene loci. These loci are called Sec1, Sec2 and Sec3. Sec1 controls expression of the traditional secretor status. Sec2 and Sec3 are linked, but distinct, loci controlling the expression of low molecular weight ABH substance in human saliva. A dominant mode of inheritance for the Sec2 and Sec3 systems is described.

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THE GENETICS OF AN EXPANDED SECRETOR SYSTEM

Abstract

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