The impact of bowel preparation on the severity of anastomotic leak in colon cancer patients

Ivy N. Haskins, James W. Fleshman, Richard L. Amdur, Samir Agarwal

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


Background and Objectives: The routine use of preoperative bowel preparation (BP) is heavily debated in the colorectal surgery literature. To date, no study has investigated the effect preoperative BP has on patients with an established anastomotic leak. We therefore seek to compare the severity of patient morbidity and mortality in patients with a known anastomotic leak based on type of preoperative BP using the Targeted Colectomy American College of Surgeons National Surgery Quality Improvement Program (ACS-NSQIP). Methods: All elective colon cancer operations performed with primary anastomosis were identified within the targeted colectomy database from 2012 to 2013. Patients who experienced a postoperative anastomotic leak were identified and stratified based on preoperative BP. Variables that had an association with mechanical BP at P < 0.10 were included in a multivariate logistic regression model to determine if BP was independently associated with postoperative morbidity and mortality. Results: A total of 6,297 patients underwent elective colon resection with primary anastomosis for colon cancer. Two hundred and nineteen (3.5%) patients experienced an anastomotic leak. Thirty-day wound morbidity and mortality was not worse in patients who underwent preoperative BP. Conclusions: BP is not associated with worse patients outcomes in those patients with an established anastomotic leak following elective colon research with primary anastomosis. J. Surg. Oncol. 2016;114:810–813.

Original languageEnglish (US)
Pages (from-to)810-813
Number of pages4
JournalJournal of Surgical Oncology
Issue number7
StatePublished - Dec 1 2016
Externally publishedYes


  • anastomotic leak
  • bowel preparation
  • colectomy
  • colon cancer

ASJC Scopus subject areas

  • Surgery
  • Oncology


Dive into the research topics of 'The impact of bowel preparation on the severity of anastomotic leak in colon cancer patients'. Together they form a unique fingerprint.

Cite this