The inheritance of psoriasis

W. Kimberling, R. L. Dobson

Research output: Contribution to journalArticle

26 Scopus citations

Abstract

Although a number of modes of genetic transmission have been proposed in psoriasis, an autosomal dominant pattern seems most consistent with available data. This suggests that an abnormality in a structural protein may be the underlying defect in the disease. The recent finding of a possible defect in the adenyl cyclase cyclic AMP cascade in the psoriatic epidermis suggests that a receptor site on the basal cell surface is a likely place to search for an altered protein.

Original languageEnglish (US)
Pages (from-to)538-540
Number of pages3
JournalJournal of Investigative Dermatology
Volume60
Issue number6
DOIs
StatePublished - 1973
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Dermatology
  • Cell Biology

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