Abstract
Although a number of modes of genetic transmission have been proposed in psoriasis, an autosomal dominant pattern seems most consistent with available data. This suggests that an abnormality in a structural protein may be the underlying defect in the disease. The recent finding of a possible defect in the adenyl cyclase cyclic AMP cascade in the psoriatic epidermis suggests that a receptor site on the basal cell surface is a likely place to search for an altered protein.
Original language | English (US) |
---|---|
Pages (from-to) | 538-540 |
Number of pages | 3 |
Journal | Journal of Investigative Dermatology |
Volume | 60 |
Issue number | 6 |
DOIs | |
State | Published - 1973 |
Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry
- Molecular Biology
- Dermatology
- Cell Biology