Abstract
This review summarizes current knowledge of the biology, pathology and clinical understanding of lymphatic invasion and metastasis in pancreatic cancer. We discuss the clinical and biological consequences of lymphatic invasion and metastasis, including paraneoplastic effects on immune responses and consider the possible benefit of therapies to treat tumors that are localized to lymphatics. A review of current techniques and methods to study interactions between tumors and lymphatics is presented.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 217-236 |
| Number of pages | 20 |
| Journal | Cancer Letters |
| Volume | 381 |
| Issue number | 1 |
| DOIs | |
| State | Published - Oct 10 2016 |
Keywords
- Lymph node
- Lymphatics
- Pancreatic cancer
ASJC Scopus subject areas
- Oncology
- Cancer Research
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Cite this
Fink, D. M., Steele, M. M., & Hollingsworth, M. A. (2016). The lymphatic system and pancreatic cancer. Cancer Letters, 381(1), 217-236. https://doi.org/10.1016/j.canlet.2015.11.048