The lymphatic system and pancreatic cancer

Darci M. Fink, Maria M. Steele, Michael A. Hollingsworth

Research output: Contribution to journalReview article

14 Scopus citations

Abstract

This review summarizes current knowledge of the biology, pathology and clinical understanding of lymphatic invasion and metastasis in pancreatic cancer. We discuss the clinical and biological consequences of lymphatic invasion and metastasis, including paraneoplastic effects on immune responses and consider the possible benefit of therapies to treat tumors that are localized to lymphatics. A review of current techniques and methods to study interactions between tumors and lymphatics is presented.

Original languageEnglish (US)
Pages (from-to)217-236
Number of pages20
JournalCancer Letters
Volume381
Issue number1
DOIs
StatePublished - Oct 10 2016

Keywords

  • Lymph node
  • Lymphatics
  • Pancreatic cancer

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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