The marmoset as a model in behavioral neuroscience and psychiatric research

Jeffrey A. French

doi:10.1016/B978-0-12-811829-0.00026-1

The marmoset as a model in behavioral neuroscience and psychiatric research

Jeffrey A. French

Research output: Chapter in Book/Report/Conference proceeding › Chapter

7 Scopus citations

Abstract

Psychological disorders and the brain mechanisms underlying them are a central focus in biomedical research. This chapter explores the rationale for marmosets as useful models for addressing these questions and discusses exemplars of behavioral protocols in five major “Domains” of psychological and behavioral functions, within the context of the NIMH’s Research Domain Criteria (RDoC) framework. The marmoset models reveal much about the regulatory processes that mediate and modulate normal behavioral functioning. Furthermore, research with marmosets highlights structural and functional systems that may underlie psychopathology and point to treatment modalities that may ameliorate these conditions.

Original language	English (US)
Title of host publication	The Common Marmoset in Captivity and Biomedical Research
Publisher	Elsevier
Pages	477-491
Number of pages	15
ISBN (Electronic)	9780128118290
ISBN (Print)	9780128118306
DOIs	https://doi.org/10.1016/B978-0-12-811829-0.00026-1
State	Published - Jan 1 2018

Keywords

Behavioral models
Circadian rhythms
Fear/anxiety
Learning and cognition
Social behavior

ASJC Scopus subject areas

General Agricultural and Biological Sciences
General Biochemistry, Genetics and Molecular Biology

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10.1016/B978-0-12-811829-0.00026-1

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AB - Psychological disorders and the brain mechanisms underlying them are a central focus in biomedical research. This chapter explores the rationale for marmosets as useful models for addressing these questions and discusses exemplars of behavioral protocols in five major “Domains” of psychological and behavioral functions, within the context of the NIMH’s Research Domain Criteria (RDoC) framework. The marmoset models reveal much about the regulatory processes that mediate and modulate normal behavioral functioning. Furthermore, research with marmosets highlights structural and functional systems that may underlie psychopathology and point to treatment modalities that may ameliorate these conditions.

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KW - Fear/anxiety

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KW - Social behavior

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M3 - Chapter

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BT - The Common Marmoset in Captivity and Biomedical Research

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ER -

The marmoset as a model in behavioral neuroscience and psychiatric research

Abstract

Keywords

ASJC Scopus subject areas

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