The methylation of DNA in regenerating rat liver

T. A. Lawson

doi:10.1007/BF00285327

The methylation of DNA in regenerating rat liver

T. A. Lawson

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

There was more persistent methylation of liver DNA from rats given [¹⁴C] DMN if it was given during liver regeneration, either after partial hepatectomy or a dose of CCl₄ compared to otherwise untreated rats. During liver regeneration, DMN metabolism was slowed making the active metabolites available for longer.

Original language	English (US)
Pages (from-to)	211-214
Number of pages	4
Journal	Zeitschrift für Krebsforschung und Klinische Onkologie
Volume	90
Issue number	2
DOIs	https://doi.org/10.1007/BF00285327
State	Published - Jan 1977
Externally published	Yes

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1007/BF00285327

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title = "The methylation of DNA in regenerating rat liver",

abstract = "There was more persistent methylation of liver DNA from rats given [14C] DMN if it was given during liver regeneration, either after partial hepatectomy or a dose of CCl4 compared to otherwise untreated rats. During liver regeneration, DMN metabolism was slowed making the active metabolites available for longer.",

author = "Lawson, {T. A.}",

year = "1977",

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doi = "10.1007/BF00285327",

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AB - There was more persistent methylation of liver DNA from rats given [14C] DMN if it was given during liver regeneration, either after partial hepatectomy or a dose of CCl4 compared to otherwise untreated rats. During liver regeneration, DMN metabolism was slowed making the active metabolites available for longer.

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The methylation of DNA in regenerating rat liver

Abstract

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