The personality assessment inventory as a tool for diagnosing psychogenic nonepileptic seizures

Alexander W. Thompson, Nathan Hantke, Vaishali Phatak, Naomi Chaytor

Research output: Contribution to journalArticle

30 Scopus citations

Abstract

Using 184 subjects with valid personality assessment interview (PAI) profiles and video-electroencephalography (VEEG)-confirmed diagnoses of epileptic seizures (ES; n = 109) or psychogenic nonepileptic seizures (PNES; n = 75), we present the diagnostic test performance of the PAI PNES Indicator and other PAI scales when used to differentiate PNES from ES. Subjects with PNES reported significantly higher somatic, conversion, depressed, anxious, and suicidal symptoms. As a diagnostic tool, the PNES Indicator does not add additional accuracy beyond the conversion subscale (SOM-C). The somatization (SOM-S) and physiological depression (DEP-P) subscales perform as well as the SOM-C subscale. The SOM-C scale (cut point ≥70) was 58.7% sensitive and 83.5% specific at diagnosing PNES. Assuming a 30% prevalence of PNES, the SOM-C scale has a positive predictive value (PPV) of 60.4% and negative predictive value (NPV) of 82.5%. Overall, the PAI SOM-C subscale does not appear more accurate than other psychometric tests used to differentiate PNES from ES.

Original languageEnglish (US)
Pages (from-to)161-164
Number of pages4
JournalEpilepsia
Volume51
Issue number1
DOIs
StatePublished - 2010

Keywords

  • Diagnosis
  • PAI
  • Pseudoseizures
  • Somatoform disorders

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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