Abstract
Mouse Pvt-1 and rat MIS1 are frequent proviral integration sites in retrovirally induced lymphomas. The Pvt-1 locus is also involved in mouse plasmacytoma (6; 15) and in the variant Burkitt lymphoma (2;8) translocations. We show that the Pvt-l/M\SI locus is syntenic with MYC on rat chromosome 7. This is consistent with a postulate of close linkage and, possibly, a functional relationship between the MYC protooncogene and the MIS1/Pvt-1 locus.
Original language | English (US) |
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Pages (from-to) | 174-176 |
Number of pages | 3 |
Journal | Cytogenetics and Cell Genetics |
Volume | 45 |
Issue number | 3-4 |
DOIs | |
State | Published - 1987 |
Externally published | Yes |
ASJC Scopus subject areas
- Genetics
- Cell Biology