Abstract
The objective of this article is to review the literature regarding the risk of sudden infant death syndrome (SIDS) in bottle-fed infants compared to those that are breastfed. A meta-analysis and qualitative literature review were performed. Cohort and case-control studies were included if they met a minimum SIDS definition and presented data allowing calculation of an odds ratio (OR). Twenty-three studies were included in the meta-analysis. The studies were heterogeneous, and a majority (14) were of "fair" or "poor" quality. Crude ORs from 19 individual studies favored breastfeeding as protective against SIDS. The combined analysis indicated that bottle-fed infants were twice as likely to die from SIDS (pooled OR = 2.11;95% CI 1.66-2.68). The results of the analysis show that there is an association between bottle-feeding and SIDS, but this may be related to confounding variables.
Original language | English (US) |
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Pages (from-to) | 13-20 |
Number of pages | 8 |
Journal | Journal of Human Lactation |
Volume | 16 |
Issue number | 1 |
DOIs | |
State | Published - Feb 2000 |
Keywords
- Breastfeeding
- Infant nutrition
- Meta-analysis
- Sudden infant death syndrome
ASJC Scopus subject areas
- Obstetrics and Gynecology