The sonographic evaluation of lissencephaly

Brandy Sundberg, Kim Michael, Jody Berg

Research output: Contribution to journalArticlepeer-review

Abstract

Lissencephaly is a neural disorder characterized by lack of sulcations in the brain. In lissencephaly, the normal migration of the neuron does not occur due to an insult to the fetus early in gestation. This causes a "smooth brain" appearance. Lissencephaly is associated with syndromes such as Walker-Warburg and Miller-Dieker syndromes. Sonographic findings of lissencephaly include agenesis of the corpus collosum, dilated third ventricle, and lack of sulcations. Patients diagnosed with lissencephaly do not usually develop intellectually past the three- to five-month age level.

Original languageEnglish (US)
Pages (from-to)299-302
Number of pages4
JournalJournal of Diagnostic Medical Sonography
Volume19
Issue number5
DOIs
StatePublished - Sep 2003
Externally publishedYes

Keywords

  • Lissencephaly
  • Miller-Dieker syndrome
  • Sonography
  • Walker-Warburg syndrome

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

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