Abstract
The spin trap 3,3,5,5-tetramethylpyrroline-N-oxide (M4PO) reacts with superoxide to produce a short-lived spin adduct (M4PO/·OOH, AN = 14.0 G, AH = 6.5 G) that decays by a first-order process (t 1 2 ≈ 35 s at pH 7.4). This short lifetime may limit its usefulness in studies of superoxide.
Original language | English (US) |
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Pages (from-to) | 57-60 |
Number of pages | 4 |
Journal | Free Radical Biology and Medicine |
Volume | 8 |
Issue number | 1 |
DOIs | |
State | Published - 1990 |
Externally published | Yes |
Keywords
- 3,3,5-5-Tetramethylpyrroline-N-oxide (MPO)
- Free radicals
- Hydrated electron
- Hydroxyl radical
- Spin trapping
- Superoxide
ASJC Scopus subject areas
- Biochemistry
- Physiology (medical)