The Spitzenkörper: A signalling hub for the control of fungal development?

Steven D. Harris

Research output: Contribution to journalComment/debatepeer-review

26 Scopus citations


In Aspergillus nidulans, asexual development culminates in the formation of a multicellular conidiophore that bears spores known as conidia. Although several factors required for conidiophore formation have been characterized, the mechanisms underlying the transition from vegetative growth to development remain obscure. However, the recent characterization of two of these factors, FIbB and FIbE, provides important new insight. Notably, these studies suggest that the Spitzenkörper (i.e. apical body), which is known to regulate hyphal morphogenesis, might also serve as a signalling hub that co-ordinates development transitions.

Original languageEnglish (US)
Pages (from-to)733-736
Number of pages4
JournalMolecular Microbiology
Issue number5
StatePublished - Sep 2009

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology


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