TY - JOUR
T1 - The Spitzenkörper
T2 - A signalling hub for the control of fungal development?
AU - Harris, Steven D.
PY - 2009/9
Y1 - 2009/9
N2 - In Aspergillus nidulans, asexual development culminates in the formation of a multicellular conidiophore that bears spores known as conidia. Although several factors required for conidiophore formation have been characterized, the mechanisms underlying the transition from vegetative growth to development remain obscure. However, the recent characterization of two of these factors, FIbB and FIbE, provides important new insight. Notably, these studies suggest that the Spitzenkörper (i.e. apical body), which is known to regulate hyphal morphogenesis, might also serve as a signalling hub that co-ordinates development transitions.
AB - In Aspergillus nidulans, asexual development culminates in the formation of a multicellular conidiophore that bears spores known as conidia. Although several factors required for conidiophore formation have been characterized, the mechanisms underlying the transition from vegetative growth to development remain obscure. However, the recent characterization of two of these factors, FIbB and FIbE, provides important new insight. Notably, these studies suggest that the Spitzenkörper (i.e. apical body), which is known to regulate hyphal morphogenesis, might also serve as a signalling hub that co-ordinates development transitions.
UR - http://www.scopus.com/inward/record.url?scp=70350149541&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=70350149541&partnerID=8YFLogxK
U2 - 10.1111/j.1365-2958.2009.06803.x
DO - 10.1111/j.1365-2958.2009.06803.x
M3 - Comment/debate
C2 - 19627503
AN - SCOPUS:70350149541
SN - 0950-382X
VL - 73
SP - 733
EP - 736
JO - Molecular Microbiology
JF - Molecular Microbiology
IS - 5
ER -