Abstract
Tandem mass spectrometry was used in the structure determinations of adducts formed between nucleosides and the potent carcinogen dibenzo[a,l]pyrene. Adducts expected to arise from both the one-electron oxidation mechanism and by the diol epoxide mechanism were studied. Structural isomers of the adducts can be distinguished by the fragment ions observed in their respective collisionally activated decomposition (CAD) spectra.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 215-222 |
| Number of pages | 8 |
| Journal | Polycyclic Aromatic Compounds |
| Volume | 6 |
| Issue number | 1-4 |
| DOIs | |
| State | Published - Jan 1994 |
Keywords
- FAB
- MS/MS
- PAH-DNA adducts
- mass spectrometry
ASJC Scopus subject areas
- Polymers and Plastics
- Organic Chemistry
- Materials Chemistry
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Cite this
Cerny, R. L., Wellemans, J. M. Y., George, M., & Gross, M. L. (1994). The use of tandem mass spectrometry for the structure determination of adducts formed between dna and dibenzo[a, l]pyrene. Polycyclic Aromatic Compounds, 6(1-4), 215-222. https://doi.org/10.1080/10406639408031187