TY - JOUR
T1 - The use of two-dimensional gas chromatography-time-of-flight mass spectrometry (GC×GC-TOF-MS) for metabolomic analysis of polar metabolites.
AU - Ralston-Hooper, Kimberly
AU - Jannasch, Amber
AU - Adamec, Jiri
AU - Sepúlveda, Maria
PY - 2011
Y1 - 2011
N2 - Metabolites produced by an organism can be quite extensive, and one analytical technique alone is not capable of their comprehensive detection and identification. The majority of environmental metabolomic studies have implemented proton nuclear magnetic resonance ((1)H-NMR) spectroscopy with little attention given to mass spectrometry (MS) techniques. In this chapter, an analytical technique is outlined that incorporates two-dimensional gas chromatography-time-of-flight MS (GC×GC-TOF-MS) for the identification and quantification of polar metabolites.
AB - Metabolites produced by an organism can be quite extensive, and one analytical technique alone is not capable of their comprehensive detection and identification. The majority of environmental metabolomic studies have implemented proton nuclear magnetic resonance ((1)H-NMR) spectroscopy with little attention given to mass spectrometry (MS) techniques. In this chapter, an analytical technique is outlined that incorporates two-dimensional gas chromatography-time-of-flight MS (GC×GC-TOF-MS) for the identification and quantification of polar metabolites.
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U2 - 10.1007/978-1-61737-985-7_12
DO - 10.1007/978-1-61737-985-7_12
M3 - Article
C2 - 21207292
AN - SCOPUS:79953741226
VL - 708
SP - 205
EP - 211
JO - Methods in molecular biology (Clifton, N.J.)
JF - Methods in molecular biology (Clifton, N.J.)
SN - 1064-3745
ER -