Therapeutic studies in NZB/NZW mice.

Alfred D. Steinberg, Randall Krakauer, James L. Reinertsen, Lynell W. Klassen, David Ilfeld, J. Patton Reeves, Gary W. Williams, Tatiana Antonovych

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

Spleen cells from normal mice were cultured with Concanavalin A to produce an immunosuppressive supernate. This supernate was used to treat the lupus‐like autoimmune disease of NZB/NZW mice. Such treated mice lived significantly longer than did controls, but only if treatment was initiated early in the course of the illness.

Original languageEnglish (US)
Pages (from-to)204-209
Number of pages6
JournalArthritis & Rheumatism
Volume21
Issue number2
DOIs
StatePublished - Mar 1978
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Rheumatology
  • Immunology
  • Pharmacology (medical)

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