Thymoma in the offspring of a patient with Isaacs syndrome

Don Coulter, Stuart Gold

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Thymoma is a diagnosis most often made in adults, and is exceedingly rare in children. The diagnosis of a thymoma is often times linked to an autoimmune process, and the association of thymoma and myasthenia gravis in children has been previously reported. We present the first description of a child of a parent with Isaacs syndrome (congenital or acquired neuromyotonia) presenting with a thymoma. In our patient, an evaluation of underlying disease led to a presumptive diagnosis of congenital Isaacs syndrome. This case demonstrates that for the rare child diagnosed with thymoma, evaluation for an underlying neurologic disorder should be considered.

Original languageEnglish (US)
Pages (from-to)797-798
Number of pages2
JournalJournal of Pediatric Hematology/Oncology
Issue number11
StatePublished - Nov 2007
Externally publishedYes


  • Autoimmune
  • Isaacs syndrome
  • Thymoma

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology


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