Abstract
Six genetically related Shorthorn calves were affected with the tibial hemimelia syndrome. The lesions included bilaterally malformed or absent tibia and abdominal hernia in all animals, a long shaggy haircoat, retained testicles in males, and meningocele in three animals. The malformations were similar to those described previously in Galloway calves. Pedigree analysis demonstrated a mechanism by which a recessive allele in a homozygous state could be responsible for the disorder. The condition in these calves was considered the result of a recurrence of a genetic mutation affecting a putative hemimelia locus.
Original language | English (US) |
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Pages (from-to) | 508-511 |
Number of pages | 4 |
Journal | Veterinary pathology |
Volume | 37 |
Issue number | 5 |
DOIs | |
State | Published - Sep 2000 |
Externally published | Yes |
Keywords
- Cattle
- Congenital disorder
- Hemimelia
- Hereditary disease
- Meningocele
- Musculoskeletal system
- Skull
- Tibia
- Ventral hernia
ASJC Scopus subject areas
- veterinary(all)