Total body water changes after an exercise intervention tracked using bioimpedance spectroscopy: A deuterium oxide comparison

Jordan R. Moon, Abbie E. Smith, Sarah E. Tobkin, Christopher M. Lockwood, Kristina L. Kendall, Jennifer L. Graef, Michael D. Roberts, Vincent J. Dalbo, Chad M. Kerksick, Joel T. Cramer, Travis W. Beck, Jeffrey R. Stout

Research output: Contribution to journalArticlepeer-review

41 Scopus citations


Background & aims: Bioimpedance spectroscopy (BIS) for the estimation of total body water (TBW) has advantages over isotope dilution techniques, including cost, portability, and ease of use. The aim of the current study was to determine the validity of a BIS device (Imp™ SFB7) for tracking changes in overfat and obese individuals. Methods: Sixty overfat and obese men and women (27 ± 8 yr, 33.41 ± 3.81%fat) participated in the study. TBW was estimated using BIS and deuterium oxide (D2O) before and after the ten-week intervention. Results: Pre-and post-intervention BIS TBW estimations errors increased as body mass index (BMI), fat mass (FM), and fat-free mass (FFM) increased (p < 0.05). Delta values were more accurate than pre- and post-TBW estimations (total error = 1.45 L). Age significantly influenced pre- and post-TBW errors (p < 0.05). Therefore, a regression equation was developed to correct for the pre- and post-BIS-estimated TBW errors: D2O TBW = 11.478 + 0.743(BIS TBW)-2.429(Gender), (Men = 1, Women = 2). Conclusions: BIS can be considered an accurate tool for tracking changes in TBW regardless of variations in BMI, FM, FFM, or age in both overfat and obese men and women (BMI > 24). Employing a BIS TBW equation is suggested over the development of resistivity coefficients based on BMI, FM, FFM or age.

Original languageEnglish (US)
Pages (from-to)516-525
Number of pages10
JournalClinical Nutrition
Issue number5
StatePublished - Oct 2009
Externally publishedYes


  • Body composition
  • Body fat
  • Deuterium oxide
  • Exercise intervention
  • Extracellular water
  • Overfat

ASJC Scopus subject areas

  • Nutrition and Dietetics
  • Critical Care and Intensive Care Medicine


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