Abstract
Transannular reductive rearrangement of bridged cyclic α-amino ketones led to the aza-tricyclic frameworks azepinoindole, hydrolulolidine, and hydrojulolidine of the typical alkaloids of Stemona, Aspidosperma, and Lycopodium, respectively. This facile approach demonstrates the potential applicability of the Clemmensen-Clemo-Prelog-Leonard reductive rearrangement of tricyclic α-amino ketones for the aza-heterocycle synthesis.
Original language | English (US) |
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Pages (from-to) | 6154-6162 |
Number of pages | 9 |
Journal | Journal of Organic Chemistry |
Volume | 78 |
Issue number | 12 |
DOIs | |
State | Published - Jun 21 2013 |
Externally published | Yes |
ASJC Scopus subject areas
- Organic Chemistry