Transcriptional Profiling During Neural Conversion

Yohannes Afeworki, Hannah Wollenzien, Michael S. Kareta

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The processes that underlie neuronal conversion ultimately involve a reorganization of transcriptional networks to establish a neuronal cell fate. As such, transcriptional profiling is a key component toward understanding this process. In this chapter, we will discuss methods of elucidating transcriptional networks during neuronal reprogramming and considerations that should be incorporated in experimental design.

Original languageEnglish (US)
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages171-181
Number of pages11
DOIs
StatePublished - 2021

Publication series

NameMethods in Molecular Biology
Volume2352
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029

Keywords

  • Induced neurons
  • Neuronal conversion
  • RNA-seq
  • Transcriptional profiling

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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