Transgenes in autoimmunity

Myung Shik Lee; Nora Sarvetnick

doi:10.1016/0952-7915(92)90052-G

Transgenes in autoimmunity

Myung Shik Lee, Nora Sarvetnick

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

The ability of transgenic mice to express a specific protein in a specific tissue has enabled the mechanisms of self-tolerance and autoimmunity to be elucidated. Further studies, combined with more sophisticated methods of gene targeting, will provide insights into the pathway leading from loss of self-tolerance to autoimmunity.

Original language	English (US)
Pages (from-to)	723-727
Number of pages	5
Journal	Current Opinion in Immunology
Volume	4
Issue number	6
DOIs	https://doi.org/10.1016/0952-7915(92)90052-G
State	Published - Dec 1992

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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title = "Transgenes in autoimmunity",

abstract = "The ability of transgenic mice to express a specific protein in a specific tissue has enabled the mechanisms of self-tolerance and autoimmunity to be elucidated. Further studies, combined with more sophisticated methods of gene targeting, will provide insights into the pathway leading from loss of self-tolerance to autoimmunity.",

author = "Lee, {Myung Shik} and Nora Sarvetnick",

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AB - The ability of transgenic mice to express a specific protein in a specific tissue has enabled the mechanisms of self-tolerance and autoimmunity to be elucidated. Further studies, combined with more sophisticated methods of gene targeting, will provide insights into the pathway leading from loss of self-tolerance to autoimmunity.

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