Abstract
The ability of transgenic mice to express a specific protein in a specific tissue has enabled the mechanisms of self-tolerance and autoimmunity to be elucidated. Further studies, combined with more sophisticated methods of gene targeting, will provide insights into the pathway leading from loss of self-tolerance to autoimmunity.
Original language | English (US) |
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Pages (from-to) | 723-727 |
Number of pages | 5 |
Journal | Current Opinion in Immunology |
Volume | 4 |
Issue number | 6 |
DOIs | |
State | Published - Dec 1992 |
Externally published | Yes |
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology