Transgenes in autoimmunity

Myung Shik Lee, Nora Sarvetnick

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


The ability of transgenic mice to express a specific protein in a specific tissue has enabled the mechanisms of self-tolerance and autoimmunity to be elucidated. Further studies, combined with more sophisticated methods of gene targeting, will provide insights into the pathway leading from loss of self-tolerance to autoimmunity.

Original languageEnglish (US)
Pages (from-to)723-727
Number of pages5
JournalCurrent Opinion in Immunology
Issue number6
StatePublished - Dec 1992
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


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