Abstract
Nonossifying fibroma is a benign, lytic lesion of fibrous origin most often observed in the metaphyseal region of the long bones in children and adolescents. It is frequently asymptomatic and is often characterized by a history of spontaneous resolution. Herein, we report a clinicohistopathologically typical case of nonossifying fibroma arising in the tibia of an 18-year-old skeletally mature female. Conventional cytogenetic analysis revealed a reciprocal translocation involving bands 1p31 and 4q34 [t(1;4)(p31;q34)]. To the best of our knowledge, this is only the second reported case of a clonally aberrant nonossifying fibroma.
Original language | English (US) |
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Pages (from-to) | 142-144 |
Number of pages | 3 |
Journal | Cancer genetics and cytogenetics |
Volume | 142 |
Issue number | 2 |
DOIs | |
State | Published - Apr 15 2003 |
ASJC Scopus subject areas
- Molecular Biology
- Genetics
- Cancer Research