Translocation (2;11)(q31;q12) is recurrent in collagenous fibroma (desmoplastic fibroblastoma)

Kerry Bernal; Marilu Nelson; James R. Neff; Stephen M. Nielsen; Julia A. Bridge

doi:10.1016/S0165-4608(03)00298-X

Translocation (2;11)(q31;q12) is recurrent in collagenous fibroma (desmoplastic fibroblastoma)

Kerry Bernal, Marilu Nelson, James R. Neff, Stephen M. Nielsen, Julia A. Bridge

Pathology & Microbiology

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

Collagenous fibroma (desmoplastic fibroblastoma) is a rare, benign tumor composed of spindle and stellate-shaped fibroblasts and myofibroblasts in a densely collagenous background. A t(2;11)(q31;q12) has been reported in one case of collagenous fibroma and a rearrangement of the 11q12 breakpoint in a second case. In the present study, we detected a t(2;11) identical to that previously described in a collagenous fibroma arising in the supraclavicular fossa of a 55-year-old man. This finding confirms the nonrandom association of t(2;11)(q31;q12) with collagenous fibroma.

Original language	English (US)
Pages (from-to)	161-163
Number of pages	3
Journal	Cancer genetics and cytogenetics
Volume	149
Issue number	2
DOIs	https://doi.org/10.1016/S0165-4608(03)00298-X
State	Published - Mar 2004

ASJC Scopus subject areas

Molecular Biology
Genetics
Cancer Research

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title = "Translocation (2;11)(q31;q12) is recurrent in collagenous fibroma (desmoplastic fibroblastoma)",

abstract = "Collagenous fibroma (desmoplastic fibroblastoma) is a rare, benign tumor composed of spindle and stellate-shaped fibroblasts and myofibroblasts in a densely collagenous background. A t(2;11)(q31;q12) has been reported in one case of collagenous fibroma and a rearrangement of the 11q12 breakpoint in a second case. In the present study, we detected a t(2;11) identical to that previously described in a collagenous fibroma arising in the supraclavicular fossa of a 55-year-old man. This finding confirms the nonrandom association of t(2;11)(q31;q12) with collagenous fibroma.",

author = "Kerry Bernal and Marilu Nelson and Neff, {James R.} and Nielsen, {Stephen M.} and Bridge, {Julia A.}",

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T1 - Translocation (2;11)(q31;q12) is recurrent in collagenous fibroma (desmoplastic fibroblastoma)

AU - Bernal, Kerry

AU - Nelson, Marilu

AU - Neff, James R.

AU - Nielsen, Stephen M.

AU - Bridge, Julia A.

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AB - Collagenous fibroma (desmoplastic fibroblastoma) is a rare, benign tumor composed of spindle and stellate-shaped fibroblasts and myofibroblasts in a densely collagenous background. A t(2;11)(q31;q12) has been reported in one case of collagenous fibroma and a rearrangement of the 11q12 breakpoint in a second case. In the present study, we detected a t(2;11) identical to that previously described in a collagenous fibroma arising in the supraclavicular fossa of a 55-year-old man. This finding confirms the nonrandom association of t(2;11)(q31;q12) with collagenous fibroma.

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