Abstract
Collagenous fibroma (desmoplastic fibroblastoma) is a rare, benign tumor composed of spindle and stellate-shaped fibroblasts and myofibroblasts in a densely collagenous background. A t(2;11)(q31;q12) has been reported in one case of collagenous fibroma and a rearrangement of the 11q12 breakpoint in a second case. In the present study, we detected a t(2;11) identical to that previously described in a collagenous fibroma arising in the supraclavicular fossa of a 55-year-old man. This finding confirms the nonrandom association of t(2;11)(q31;q12) with collagenous fibroma.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 161-163 |
| Number of pages | 3 |
| Journal | Cancer genetics and cytogenetics |
| Volume | 149 |
| Issue number | 2 |
| DOIs | |
| State | Published - Mar 2004 |
ASJC Scopus subject areas
- Molecular Biology
- Genetics
- Cancer Research
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Cite this
Bernal, K., Nelson, M., Neff, J. R., Nielsen, S. M., & Bridge, J. A. (2004). Translocation (2;11)(q31;q12) is recurrent in collagenous fibroma (desmoplastic fibroblastoma). Cancer genetics and cytogenetics, 149(2), 161-163. https://doi.org/10.1016/S0165-4608(03)00298-X