Translocation (2;11)(q31;q12) is recurrent in collagenous fibroma (desmoplastic fibroblastoma)

Kerry Bernal, Marilu Nelson, James R. Neff, Stephen M. Nielsen, Julia A. Bridge

Research output: Contribution to journalArticle

39 Scopus citations

Abstract

Collagenous fibroma (desmoplastic fibroblastoma) is a rare, benign tumor composed of spindle and stellate-shaped fibroblasts and myofibroblasts in a densely collagenous background. A t(2;11)(q31;q12) has been reported in one case of collagenous fibroma and a rearrangement of the 11q12 breakpoint in a second case. In the present study, we detected a t(2;11) identical to that previously described in a collagenous fibroma arising in the supraclavicular fossa of a 55-year-old man. This finding confirms the nonrandom association of t(2;11)(q31;q12) with collagenous fibroma.

Original languageEnglish (US)
Pages (from-to)161-163
Number of pages3
JournalCancer genetics and cytogenetics
Volume149
Issue number2
DOIs
StatePublished - Mar 2004

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research

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