Translocation (X;18) in primary synovial sarcoma of the lung

Cory A. Roberts, Thomas A. Seemayer, James R. Neff, Anselmo Alonso, Marilu Nelson, Julia A. Bridge

Research output: Contribution to journalArticlepeer-review

48 Scopus citations


Primary sarcomas of the lung are extremely rare. Among the most common to occur in this location are leiomyosarcoma, fibrosarcoma, and hemangiopericytoma. Many difficulties are encountered when establishing these sarcoma diagnoses, or one of another pathologic type, because of overlapping histologic features and morphologic similarities between primary and metastatic lesions. In this study, the diagnosis of o primary monophasic synovial sarcoma of the lung was aided by the observation of the X;18 translocation characteristic of this neoplasm. To the best of our knowledge, this is the first cytogenetic report of a primary pulmonary synovial sarcoma.

Original languageEnglish (US)
Pages (from-to)49-52
Number of pages4
JournalCancer genetics and cytogenetics
Issue number1
StatePublished - May 1996

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research

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