Transportability of a Decision Rule for the Diagnosis of Streptococcal Pharyngitis

Robert S. Wigton, James L. Connor, Robert M. Centor

Research output: Contribution to journalArticlepeer-review

90 Scopus citations


Use of existing decision rules could improve management of streptococcal pharyngitis, but the validity of such rules outside their original patient population is not known. We applied a four-item decision rule derived at the Medical College of Virginia, Richmond, to 516 patients at the University of Nebraska, Omaha, to test how accurately it would predict outcome of throat culture. After correction for differences in the prevalence of a positive culture (17% in Virginia, 26% in Nebraska), the rule closely predicted the frequency of positive cultures in five subgroups based on the presence of clinical findings. We conclude that this rule transported well to a different patient population and would have been useful in identifying patients with pharyngitis who had a high likelihood of throat cultures positive for group A streptococci.

Original languageEnglish (US)
Pages (from-to)81-83
Number of pages3
JournalArchives of Internal Medicine
Issue number1
StatePublished - Jan 1986

ASJC Scopus subject areas

  • Internal Medicine


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