TY - JOUR
T1 - Treatment of life-threatening hemangiomas of childhood
AU - Corpron, C. A.
AU - Andrassy, R. J.
AU - Singh, R. K.
AU - Ellis, L. M.
PY - 1995
Y1 - 1995
N2 - HEMANGIOMAS ARE the most common tumor of infancy. Although a majority of these tumors regress without treatment by age 10, a small percentage may cause serious complications, such as obstruction of visual, auditory, digestive or respiratory systems, ulceration and intractable pain, high output cardiac failure, and thrombocytopenia. Although options for treatment of these tumors include surgical resection, chemotherapy, embolization, laser therapy, and radiotherapy, they have been largely abandoned for corticosteroid treatment. More recently, interferon-2 alpha (IFN-2α) has been used to treat children with steroid-resistant hemangiomas and may be the choice in children with life-threatening hemangiomas.
AB - HEMANGIOMAS ARE the most common tumor of infancy. Although a majority of these tumors regress without treatment by age 10, a small percentage may cause serious complications, such as obstruction of visual, auditory, digestive or respiratory systems, ulceration and intractable pain, high output cardiac failure, and thrombocytopenia. Although options for treatment of these tumors include surgical resection, chemotherapy, embolization, laser therapy, and radiotherapy, they have been largely abandoned for corticosteroid treatment. More recently, interferon-2 alpha (IFN-2α) has been used to treat children with steroid-resistant hemangiomas and may be the choice in children with life-threatening hemangiomas.
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M3 - Review article
AN - SCOPUS:0029556937
SN - 0740-820X
VL - 47
SP - 408
EP - 411
JO - Cancer Bulletin
JF - Cancer Bulletin
IS - 5
ER -