Turn-on ratiometric fluorescent sensor for Pb2+ detection

Chen Hou, Yijia Xiong, Na Fu, Caitlin C. Jacquot, Thomas C. Squier, Haishi Cao

Research output: Contribution to journalArticlepeer-review

35 Scopus citations


We report a ratiometric lead fluorescent sensor (LFS-1) with high affinity to Pb2+ that shows considerable selectivity over 12 other physiological related metal cations in aqueous media. Binding induces excimer formation, providing a highly sensitive ratiometric measure of lead concentrations.

Original languageEnglish (US)
Pages (from-to)2692-2696
Number of pages5
JournalTetrahedron Letters
Issue number21
StatePublished - May 25 2011


  • Pb
  • Pyrene
  • Sensor

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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