TY - JOUR
T1 - Two-Photon Polymerized Shape Memory Microfibers
T2 - A New Mechanical Characterization Method in Liquid
AU - Minnick, Grayson
AU - Safa, Bahareh Tajvidi
AU - Rosenbohm, Jordan
AU - Lavrik, Nickolay V.
AU - Brooks, Justin
AU - Esfahani, Amir M.
AU - Samaniego, Alberto
AU - Meng, Fanben
AU - Richter, Benjamin
AU - Gao, Wei
AU - Yang, Ruiguo
N1 - Funding Information:
The authors thank Dr. Lei Fang from Texas A&M University for helpful discussions. The authors acknowledge the funding support from the NSF (Awards 1826135, 1936065, 2143997), the NIH National Institutes of General Medical Sciences P20GM113126 (Nebraska Center for Integrated Biomolecular Communication), and P30GM127200 (Nebraska Center for Nanomedicine), the Nebraska Collaborative Initiative, and the Voelte-Keegan Bioengineering Support. Design and fabrication of the TPP structures were conducted at the Center for Nanophase Materials Sciences (CNMS) at ORNL, which is a DOE Office of Science User Facility. Manufacturing and characterization analysis were performed at the NanoEngineering Research Core Facility (NERCF). G.M. and J.R. are funded by the NSF Graduate Research Fellowship (Award 2034837).
Funding Information:
The authors thank Dr. Lei Fang from Texas A&M University for helpful discussions. The authors acknowledge the funding support from the NSF (Awards 1826135, 1936065, 2143997), the NIH National Institutes of General Medical Sciences P20GM113126 (Nebraska Center for Integrated Biomolecular Communication), and P30GM127200 (Nebraska Center for Nanomedicine), the Nebraska Collaborative Initiative, and the Voelte‐Keegan Bioengineering Support. Design and fabrication of the TPP structures were conducted at the Center for Nanophase Materials Sciences (CNMS) at ORNL, which is a DOE Office of Science User Facility. Manufacturing and characterization analysis were performed at the NanoEngineering Research Core Facility (NERCF). G.M. and J.R. are funded by the NSF Graduate Research Fellowship (Award 2034837).
Publisher Copyright:
© 2022 The Authors. Advanced Functional Materials published by Wiley-VCH GmbH.
PY - 2022
Y1 - 2022
N2 - Two-photon polymerization (TPP) is widely used to create 3D micro- and nanoscale scaffolds for biological and mechanobiological studies, which often require the mechanical characterization of the TPP fabricated structures. To satisfy physiological requirements, most of the mechanical characterizations need to be conducted in liquid. However, previous characterizations of TPP fabricated structures are all conducted in air due to the limitation of conventional micro- and nanoscale mechanical testing methods. In this study, a new experimental method is reported for testing the mechanical properties of TPP-printed microfibers in liquid. The experiments show that the mechanical behaviors of the microfibers tested in liquid are significantly different from those tested in air. By controlling the TPP writing parameters, the mechanical properties of the microfibers can be tailored over a wide range to meet a variety of mechanobiology applications. In addition, it is found that, in water, the plasticly deformed microfibers can return to their predeformed shape after tensile strain is released. The shape recovery time is dependent on the size of microfibers. The experimental method represents a significant advancement in mechanical testing of TPP fabricated structures and may help release the full potential of TPP fabricated 3D tissue scaffolds for mechanobiological studies.
AB - Two-photon polymerization (TPP) is widely used to create 3D micro- and nanoscale scaffolds for biological and mechanobiological studies, which often require the mechanical characterization of the TPP fabricated structures. To satisfy physiological requirements, most of the mechanical characterizations need to be conducted in liquid. However, previous characterizations of TPP fabricated structures are all conducted in air due to the limitation of conventional micro- and nanoscale mechanical testing methods. In this study, a new experimental method is reported for testing the mechanical properties of TPP-printed microfibers in liquid. The experiments show that the mechanical behaviors of the microfibers tested in liquid are significantly different from those tested in air. By controlling the TPP writing parameters, the mechanical properties of the microfibers can be tailored over a wide range to meet a variety of mechanobiology applications. In addition, it is found that, in water, the plasticly deformed microfibers can return to their predeformed shape after tensile strain is released. The shape recovery time is dependent on the size of microfibers. The experimental method represents a significant advancement in mechanical testing of TPP fabricated structures and may help release the full potential of TPP fabricated 3D tissue scaffolds for mechanobiological studies.
KW - IP-Visio
KW - mechanical characterization
KW - shape memory
KW - tensile testing
KW - two-photon polymerization
UR - http://www.scopus.com/inward/record.url?scp=85138571262&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85138571262&partnerID=8YFLogxK
U2 - 10.1002/adfm.202206739
DO - 10.1002/adfm.202206739
M3 - Article
C2 - 36817407
AN - SCOPUS:85138571262
SN - 1616-301X
JO - Advanced Functional Materials
JF - Advanced Functional Materials
ER -