Typhlitis in acute leukemia. Successful treatment by early surgical intervention

Ajit P. Varki, James O. Armitage, John R. Feagler

Research output: Contribution to journalArticlepeer-review

95 Scopus citations


Inflammation of the cecum (“typhlitis”) has been an unusual, but generally fatal complication of severe granulocytopenia and immunosuppresion, occurring during the therapy of hematological malignancies. The diagnosis has usually been made only at autopsy, and early surgical intervention has often been withheld because of the patient's precarious hematological status. We report here a patient in whom the clinical diagnosis of typhlitis led to early operation, with intensive blood component support. The successful outcome suggests that such an approach might improve the usually grim prognosis in patients whose underlying malignancy offers a clear chance for remission. Cancer 43:695–697, 1979.

Original languageEnglish (US)
Pages (from-to)695-697
Number of pages3
Issue number2
StatePublished - Feb 1979

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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