Understanding and manipulating plant lipid composition: Metabolic engineering leads the way

Johnathan A. Napier, Richard P. Haslam, Frederic Beaudoin, Edgar B. Cahoon

Research output: Contribution to journalReview article

65 Scopus citations

Abstract

The manipulation of plant seed oil composition so as to deliver enhanced fatty acid compositions suitable for feed or fuel has long been a goal of metabolic engineers. Recent advances in our understanding of the flux of acyl-changes through different key metabolic pools such as phosphatidylcholine and diacylglycerol have allowed for more targeted interventions. When combined in iterative fashion with further lipidomic analyses, significant breakthroughs in our capacity to generate plants with novel oils have been achieved. Collectively these studies, working at the interface between metabolic engineering and synthetic biology, demonstrate the positive fundamental and applied outcomes derived from such research.

Original languageEnglish (US)
Pages (from-to)68-75
Number of pages8
JournalCurrent Opinion in Plant Biology
Volume19
DOIs
StatePublished - Jun 2014

ASJC Scopus subject areas

  • Plant Science

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