Unsuccessful dietary treatment of Sjögren-Larsson syndrome

P. D. Maaswinkel-Mooij, O. F. Brouwer, W. B. Rizzo

Research output: Contribution to journalArticlepeer-review

24 Scopus citations


We treated five children with Sjögren-Larsson syndrome. The patients, 5 months to 8 years of age, were given a low fat diet supplemented with medium-chain fatty acids. Plasma octadecanol levels remained unchanged, and skin lesions and neurologic symptoms did not abate. Two patients also failed to respond to dietary supplementation with polyunsaturated fatty acids. We conclude that dietary therapy is usually unsuccessful in patients with Sjögren-Larsson syndrome even when started in early infancy.

Original languageEnglish (US)
Pages (from-to)748-750
Number of pages3
JournalThe Journal of Pediatrics
Issue number5 PART 1
StatePublished - May 1994
Externally publishedYes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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