TY - JOUR
T1 - Unsuccessful dietary treatment of Sjögren-Larsson syndrome
AU - Maaswinkel-Mooij, P. D.
AU - Brouwer, O. F.
AU - Rizzo, W. B.
PY - 1994/5
Y1 - 1994/5
N2 - We treated five children with Sjögren-Larsson syndrome. The patients, 5 months to 8 years of age, were given a low fat diet supplemented with medium-chain fatty acids. Plasma octadecanol levels remained unchanged, and skin lesions and neurologic symptoms did not abate. Two patients also failed to respond to dietary supplementation with polyunsaturated fatty acids. We conclude that dietary therapy is usually unsuccessful in patients with Sjögren-Larsson syndrome even when started in early infancy.
AB - We treated five children with Sjögren-Larsson syndrome. The patients, 5 months to 8 years of age, were given a low fat diet supplemented with medium-chain fatty acids. Plasma octadecanol levels remained unchanged, and skin lesions and neurologic symptoms did not abate. Two patients also failed to respond to dietary supplementation with polyunsaturated fatty acids. We conclude that dietary therapy is usually unsuccessful in patients with Sjögren-Larsson syndrome even when started in early infancy.
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U2 - 10.1016/S0022-3476(05)81369-1
DO - 10.1016/S0022-3476(05)81369-1
M3 - Article
C2 - 8176565
AN - SCOPUS:0028352186
SN - 0022-3476
VL - 124
SP - 748
EP - 750
JO - The Journal of Pediatrics
JF - The Journal of Pediatrics
IS - 5 PART 1
ER -